Hyperphagia and Obesity in Na,K-ATPase α2 Subunit-Defective Mice
نویسندگان
چکیده
منابع مشابه
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Prohormone convertase 1 (PC1) mutations lead to obesity in humans. However, Pc1 knockout mice do not become obese; in fact, they are runted due to a defect in growth-hormone releasing hormone processing, leading to the speculation that PC1 subserves different functions between mouse and human. Here, we report a novel allele of mouse Pc1 (N222D) that leads to obesity, abnormal proinsulin process...
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ژورنال
عنوان ژورنال: Obesity Research
سال: 2005
ISSN: 1071-7323
DOI: 10.1038/oby.2005.204